Detalhe da pesquisa
1.
KSR2 mutations are associated with obesity, insulin resistance, and impaired cellular fuel oxidation.
Cell
; 155(4): 765-77, 2013 Nov 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-24209692
2.
The nuts and bolts of AGC protein kinases.
Nat Rev Mol Cell Biol
; 11(1): 9-22, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20027184
3.
A homozygous mutation in the TUB gene associated with retinal dystrophy and obesity.
Hum Mutat
; 35(3): 289-93, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24375934
4.
Protor-1 is required for efficient mTORC2-mediated activation of SGK1 in the kidney.
Biochem J
; 436(1): 169-79, 2011 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21413931
5.
Characterization of PF-4708671, a novel and highly specific inhibitor of p70 ribosomal S6 kinase (S6K1).
Biochem J
; 431(2): 245-55, 2010 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20704563
6.
Identification of Protor as a novel Rictor-binding component of mTOR complex-2.
Biochem J
; 405(3): 513-22, 2007 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17461779
7.
Functional characterization of obesity-associated variants involving the α and ß isoforms of human SH2B1.
Endocrinology
; 155(9): 3219-26, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24971614
8.
Human SH2B1 mutations are associated with maladaptive behaviors and obesity.
J Clin Invest
; 122(12): 4732-6, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23160192
9.
New insights into mTOR signaling: mTORC2 and beyond.
Sci Signal
; 2(67): pe27, 2009 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-19383978